Sergio Ruiz Llorente

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Sergio Ruiz Llorente

Sergio Ruiz Llorente

Sergio Ruiz Llorente


Categoría: Profesor/a Ayudante Doctor/a

Departamento: Biomedicina y Biotecnología

Correo electrónico:

Estudios

Grado en Biología (G650)

Grado en Biología Sanitaria (G651)

Grupos de Investigación

No existen datos en este apartado

Líneas de investigación del Grupo

No existen datos en este apartado

Proyectos de Investigación

No existen datos en este apartado

Libros

No existen datos en este apartado

Capítulos

  • RUIZ LLORENTE, Sergio; , Montero-Conde, C; , Ruiz-Llorente, S; , Fagin, JA; "Cáncer de Tiroides". Bases generales y moleculares del cáncer de tiroides de estirpe folicular. 2014. .
  • RUIZ LLORENTE, Sergio; , Ruiz-Llorente, S; , Robledo, M; , Cascón, A; "Spanish Society of Medical Oncology (SEOM)". Endocrine tumor syndromes. 2006. p. 447 - 473 .

Artículos

  • NAVARRO , Paloma; GRAZIOSO , Tatiana P; BARQUÍN , Arantzazu; BARBA , María; YAGÜE , Mónica; MILLAN , Carlos; LÓPEZ , Irene; SEVILLANO , Elena; QUIRALTE , Miguel; FERNÁNDEZ , Paloma; LOSADA , Diego; CALEIRAS , Eduardo; CALZAS , Julia; , Beatriz Jimenez; RUIZ LLORENTE, Sergio; JUSTO , Juan; GUERRERO , Felix; HEVIA , Vital; MARTÍN , Raquel; PÉREZ RODRÍGUEZ , Francisco José; TEJERINA , Julia; PRIETO , Mario; COMUNE , Paula; RODRÍGUEZ MORENO , Juan Francisco; GARCÍA-DONAS , Jesús; ."Multicenter study correlating molecular characteristics and clinical outcomes of cancer cases with patient-derived organoids.". (ISSN: 0392-9078). Journal of Experimental and Clinical Cancer Research. 2025 .
  • RUIZ LLORENTE, Sergio; , Quiralte, M; , Barquín, A; , Sevillano, E; , Navarro, P; , Yagüe, M; , Barba, M; , Rodríguez-Moreno, JF; , Balarezo, A; , Peinado, H; , Izquierdo, E; , García-Donas, J; , Ruiz-Llorente, S; ."Proteomic profiling of peritoneal-derived small extracelullar vesicles from ovarian cancer patients correlates with clinical outcome". The Journal of Clinical Investigation. 2024
  • RUIZ LLORENTE, Sergio; , Ruiz-Llorente, S; , Rodríguez-Moreno, JF; , de Velasco, G; , Álvarez-Fernández, C; , Collado-Martín, R; , Fernández, R; , Vázquez-Estévez, S; , Virizuela, JA; , Gajate, P; , Font, A; , Barquín, A; , Laínez, N; , Beltran, L; , Rodríguez-Antona, C; , Berraondo, P; , García-Donas, J; ."Comprehensive molecular characterization of muscle invasive bladder cancer (MIBC) treated with durvalumab and olaparib in the neoadjuvant setting: NEODURVARIB trial". Nature Medicine (enviado, datos presentados en meeting de ASCO GU-2022). 2023
  • RUIZ LLORENTE, Sergio; , Barquín, A; , Madurga, R; , Kennedy, K; , Navarro, P; , Villares, P; , Rodríguez-Antona, C; , Ruiz-Llorente, S; , Nistal, E; , Rodríguez-Moreno, M; , Yagüe, M; , Barba, M; , Zanin, M; , Berraondo, P; , García-Donas, J; ."Randomized Phase II Clinical Trial of Ruxolitinib Plus Simvastatin in COVID19 clinical outcome and cytokine evolution". En revisión, Frontiers in Immunology. 2023
  • RUIZ LLORENTE, Sergio; , Montero-Conde, C; , Leandro-García, LJ; , Martínez-Montes, A; , Martínez, P; , Moya, FJ; , Letón, R; , Gil, E; , Martínez-Puente, N; , Guadalix, S; , Currás-Freixes, M; , García-Tobar, L; , Zafrón, C; , Jordá, M; , Riesco-Eizaguirre, G; , González-García, P; , Monteagudo, M; , Torres-Pérez, R; , Ruiz-Llorente, S; , Mancikova, V; , Pérez-Martínez, M; , Pita, G; , Galofré, JC; , González-Neira, A; , Cascón, A; , Rodríguez-Antona, C; , Megías, D; , Blasco, MA; , Caleiras, E; , Rodríguez-Perales, S; , Robledo, M; ."Comprehensive molecular analysis of immortalization hallmarks in thyroid cancer reveals new prognostic markers". Clinical and Translational Medicine. 2022
  • RUIZ LLORENTE, Sergio; ."MEK inhibitors sensitivity in BRAF fusion-driven prostate cancer". (ISSN: 1699-3055). Clinical and Translational Oncology. 2022
  • RUIZ LLORENTE, Sergio; , Bote-Curiel, L; , Ruiz-Llorente, S; , Muñoz-Romero, S; , Yagüe-Fernández, M; , Barquín, A; , García-Donas, J; , Rojo-Álvarez, JL; ."Multivariate feature selection and autoencoder embeddings of ovarian cancer clinical and genetic data". (ISSN: 0957-4174). Expert Systems with Applications. 2022
  • RUIZ LLORENTE, Sergio; , Ruiz-Llorente, S; , Bote-Curiel, L; , Muñoz-Romero, S; , Yagüe-Fernández, M; , Barquín, A; , García-Donas, J; , Rojo, JL; ."A Resampling Univariate Analysis Approach to Ovarian Cancer From Clinical and Genetic Data.". (ISSN: 2169-3536). IEEE Access. 2021 , vol 9 , p. 25959 - 25972
  • RUIZ LLORENTE, Sergio; KANG , EY; GEORGE , J; POPOVIC , G; MEAGHER , NS; BOLITHON , A; TALHOUK , A; CHIU , DS; ANGLESIO , MS; DA-ANOY , A; LAMBRECHTS , D; LOVERIX , L; SIEL , O; BISINOTTO , C; , García-Donas J; , Ruiz-Llorente S; , Yagüe-Fernández M; EDWARDS , RP; ELISHAEV , E; OLAWAIYE , A; TAYLOR , S; ATASEVEN , B; DU BOIS , A; HARTER , P; LESTER , J; HOGDALL , CK; ARMASU , SM; HUANG , Y; VIERKANT , RA; WANG , C; WINHAM , SJ; HEUBLEIN , S; KOMMOS , FKF; CRAMER , DW; SASAMOTO , N; WAGENSVELD , I; LYCKE , M; PEARCE , CL; MATEOUI , C; PIKE , MC; TSENG , CC; BILIC , S; LEUNG , Y; STEWART , C; TAN , A; YU , Y; BOROS , J; BRAND , AH; HARNETT , PR; KENNEDY , CJ; NEVINS , N; MORGAN , T; FASCHING , PA; VERGOTE , I; SWERDLOW , AJ; DOS REIS , FJC; MAXWELL , GL; NEUHAUSEN , SL; , Barquín-García A; MODUGNO , F; MOYSICH , KB; CROWE , P; HIRASAWA , A; HEITZ , F; KARLAN , BY; GOODE , EL; SINN , P; HORLINGS , H; HOGDALL , E; SUNDFELDT , K; KOMMOS , S; STAEBLER , A; WU , AH; COHEN , P; DE FAZIO , A; LEE , CH; STEED , H; LE , ND; COOK , LS; RAMUS , SJ; KELEMEN , LE; KOBEL , M; ."MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high grade serous carcinoma". Virchows Archive. 2021 , vol Nov , num 15
  • RUIZ LLORENTE, Sergio; , Bote-Curiel, L; , Ruiz-Llorente, S; , Muñoz-Romero, S; , Yagüe-Fernández, M; , Barquín, A; , García-Donas, J; , Rojo-Álvarez, JL; ."Text Analytics and Mixed FeatureExtraction in Ovarian Cancer Clinical and Genetic Data.". (ISSN: 2169-3536). IEEE Access. 2021 , p. 58034 - 58051
  • RUIZ LLORENTE, Sergio; , Ruiz-Llorente, S; , Garcia-Carpizo, V; , Sarmentero, J; , Barrero, MJ; , González-Corpas, A; ."CREBBP/EP300 Bromodomain Inhibition Affects the Proliferation of AR-Positive Breast Cancer Cell Lines". (ISSN: 1541-7786). Molecular Cancer Research. 2019 , p. 720 - 730
  • RUIZ LLORENTE, Sergio; , Ruiz-Llorente, S; , Garcia-Carpizo, V; , Sarmentero, J; , Graña-Castro, O; , Barrero, MJ; , Pisano, DG; ."CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation.". Epigenetics & Chromatin. 2018 , vol 11 , num 1
  • RUIZ LLORENTE, Sergio; , Montero-Conde, C; , Leandro-García, LJ; , Chen, X; , Ruiz-Llorente, S; , Oler, G; , Ryder, M; , Landa, I; , Sánchez-Vega, FA; , La,K; , Ghossein, RA; , Bajorin, DF; , Knauf, JA; , Riordan, JD; , Dupuy, AJ; , Fagin, JA; ."Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene". PNAS. 2017 , vol 114 , num 25 , p. E4951 - E4960
  • RUIZ LLORENTE, Sergio; , Garcia-Carpizo, V; , Sarmentero, J; , Han, B; , Ruiz-Llorente, S; , Graña, O; , Pisano, DG; , Serrano, M; , Brooks, HB; , Campbell, RM; , Barrero, MJ; ."NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation.". Scientific Reports. 2016 , vol 8 , num 6 , p. 32952 -
  • RUIZ LLORENTE, Sergio; , Landa, I; , Boullosa, C; , Inglada-Perez, L; , Sastre-Perona, A; , Pastor, S; , Velázquez, A; , Ruiz-Llorente, S; , Mancikova, V; , Schiavi, F; , Marcos, R; , Malats, N; , Opocher, G; , Díaz-Uriarte, R; , Santisteban, P; , Valencia, A; , Robledo, M; ."An epistatic interaction between the PAX8 and STK17B genes in papillary thyroid cancer susceptibility". PlosOne. 2013 , vol 8 , num 9 , p. e74765 -
  • RUIZ LLORENTE, Sergio; , Montero-Conde, C; , Ruiz-Llorente, S; , Domínguez, J; , Knauf, JA; , Viale, A; , Sherman, EJ; , Ryder, M; , Ghossein, RA; , Fagin, JA; , Rosen, N; ."Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas". Cancer Discovery. 2013 , vol 3 , num 5 , p. 520 - 533
  • RUIZ LLORENTE, Sergio; , Choi, HJ; , Ruiz-Llorente, S; , Kim, TY; , Jeon, MJ; , Han, JM; , Kim, WG; , Shong, YK; , Bae Kim, W; ."Alpha-lipoic acid induces sodium iodide symporter expression in TPC-1 thyroid cancer cell line". Nucl. Med. Biol.. 2012 , vol 39 , num 8 , p. 1275 - 1280
  • RUIZ LLORENTE, Sergio; , Ruiz-Llorente, S; , Carrillo Santa de Pau, E; , Sastre-Perona, A; , Montero-Conde, C; , Gomez-Lopez, G; , Fagin, J. A; , Valencia, A; , Pisano, DG; , Santisteban, P; ."Genome-wide analysis of Pax8 binding provides new insights into thyroid functions". (ISSN: 1471-2164). BMC Genomics. 2012 , vol 13 , p. 147 - 147
  • RUIZ LLORENTE, Sergio; , Ruiz-Llorente, S (COAUTOR); , Montero-Conde, C; , Landa, I (COAUTOR); , Inglada-Perez, L; , Schiavi, F; , Leskela, S; , Pita, G; , Milne, R; , Maravall, J; , Ramos, I; , Andia, V; , Rodriguez-Poyo, P; , Jara-Albarran, A; , Meoro, A; , del Peso, C; , Arribas, L; , Iglesias, P; , Caballero, J; , Serrano, J; , Pico, A; , Pomares, F; , Gimenez, G; , Lopez-Mondejar, P; , Castello, R; , Merante-Boschin, I; , Pelizzo, MR; , Mauricio, D; , Opocher, G; , Rodríguez-Antona, C; , González-Neira, A; , Matias-Guiu, X; , Santisteban, P; , Robledo, M; ."The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors". PLoS Genet.. 2009 , vol 5 , num 9 , p. e1000637 - e1000637
  • RUIZ LLORENTE, Sergio; , Ruiz-Llorente, S; , Montero-Conde, C; , Milne, RL; , Moya, CM; , Letón, R; , Cebrian, A; , Cascón, A; , Mercadillo, F; , Landa, I; , Borrego, S; , Perez de Nanclares, G; , Alvarez-Escola, C; , Diaz-Perez, JA; , Carracedo, A; , Urioste, M; , González-Neira, A; , Benitez, J; , Santisteban, P; , Dopazo, J; , Ponder, BA; , Robledo, M; ."Association study of 69 genes in the ret pathway identifies low-penetrance loci in sporadic medullary thyroid carcinoma". Cancer Res.. 2007 , vol 67 , num 19 , p. 9561 - 9567
  • RUIZ LLORENTE, Sergio; , Cascón, A; , Montero-Conde, C; , Escobar, B; , Rodríguez-Antona, C; , Ruiz-Llorente, S; , Osorio, A; , Mercadillo, F; , Letón, R; , Campos, JM; , Garcia-Sagredo, JM; , Benitez, J; , Malumbres, M; , Robledo, M; ."Loss of the actin regulator HSPC300 results in clear cell renal cell carcinoma protection in Von Hippel-Lindau patients". Hum. Mutat.. 2007 , vol 28 , num 6 , p. 613 - 621
  • RUIZ LLORENTE, Sergio; , Cascón, A; , Montero-Conde, C; , Ruiz-Llorente, S; , Mercadillo, F; , Letón, R; , Rodríguez-Antona, C; , Martinez-Delgado, B; , Delgado, M; , Diez, A; , Rovira, A; , Diaz, JA; , Robledo, M; ."Gross SDHB deletions in patients with paraganglioma detected by multiplex PCR: a possible hot spot?". Genes Chromosomes Cancer. 2006 , vol 45 , num 3 , p. 213 - 219
  • RUIZ LLORENTE, Sergio; , Ruiz-Llorente, S (COAUTOR); , Cascon, A (COAUTOR); , Rodríguez-Perales, S; , Honrado, E; , Martinez-Ramirez, A; , Montero-Conde, C; , Letón, R; , Benitez, J; , Dopazo, J; , Cigudosa, JC; , Robledo, M; ."A novel candidate region linked to development of both pheochromocytoma and head/neck paraganglioma". Genes Chromosomes Cancer. 2005 , vol 42 , num 3 , p. 260 - 268
  • RUIZ LLORENTE, Sergio; , Cascón, A; , Cebrian, A; , Pollan, M; , Ruiz-Llorente, S; , Montero-Conde, C; , Letón, R; , Gutierrez, R; , Lesueur, F; , Milne, RL; , Gonzalez-Albarran, O; , Lucas-Morante, T; , Benitez, J; , Ponder, BA; , Robledo, M; ."Succinate dehydrogenase D variants do not constitute a risk factor for developing C cell hyperplasia or sporadic medullary thyroid carcinoma". J. Clin. Endocrinol. Metab.. 2005 , vol 90 , num 4 , p. 2127 - 2130
  • RUIZ LLORENTE, Sergio; , Ruiz-Llorente, S (COAUTOR); , Cascon, A (COAUTOR); , Fraga, M. F.; , Leton, R.; , Telleria, D.; , Sastre, J.; , Diez, JJ; , Martinez Diaz-Guerra, G; , Benitez, J; , Diaz Perez, JA; , Esteller, M; , Robledo, M; ."Genetic and epigenetic profile of sporadic pheochromocytomas". J. Med. Genet.. 2004 , vol 41 , num 3 , p. e30 - e30
  • RUIZ LLORENTE, Sergio; , Ruiz-Llorente, S; , Bravo, J; , Cebrian, A; , Cascón, A; , Pollan, M; , Telleria, D; , Letón, R; , Urioste, M; , Rodriguez-Lopez, R; , de Campos, JM; , Munoz, MJ; , Lacambra, C; , Benitez, J; , Robledo, M; ."Genetic characterization and structural analysis of VHL Spanish families to define genotype-phenotype correlations". Hum. Mutat.. 2004 , vol 23 , num 2 , p. 160 - 169
  • RUIZ LLORENTE, Sergio; , Conde, L; , Vaquerizas, JM; , Santoyo, J; , Ruiz-Llorente, S; , Al-Shahrour, F; , Robledo, M; , Dopazo, J; ."PupaSNP Finder: a web tool for finding SNPs with putative effect at transcriptional level". Nucleic Acids Res.. 2004 , vol 32 , num Web Server issue , p. W242 - 248
  • RUIZ LLORENTE, Sergio; , Robledo, M; , Fernandez, RM; , Antinolo, G; , Ruiz-Llorente, S; , Pecina, A; , Eng, C; , Borrego, S; ."The RET IVS1-126G>T variant is strongly associated with the development of sporadic medullary thyroid cancer". Thyroid. 2004 , vol 14 , num 4 , p. 329 - 331
  • RUIZ LLORENTE, Sergio; , Ruiz-Llorente, S (COAUTOR); , Cascon, A (COAUTOR); , Cebrian, A; , Letón, R; , Telleria, D; , Robledo, M; , Benitez, J; ."G12S and H50R variations are polymorphisms in the SDHD gene". Genes Chromosomes Cancer. 2003 , vol 37 , num 2 , p. 220 - 221
  • RUIZ LLORENTE, Sergio; , Rodríguez-Perales, S; , Melendez, B; , Martinez-Delgado, B; , Robledo, M; , Otero, I; , Martinez-Ramirez, A; , Ruiz-Llorente, S; , Urioste, M; , Cigudosa, JC; , Benitez, J; ."Molecular study of a new family with hereditary renal cell carcinoma and a translocation t(3;8)(p13;q24.1)". Hum. Genet.. 2003 , vol 112 , num 2 , p. 178 - 185
  • RUIZ LLORENTE, Sergio; , Cebrian, A; , Ruiz-Llorente, S; , Cascón, A; , Pollan, M; , Diez, JJ; , Pico, A; , Telleria, D; , Benitez, J; , Robledo, M; ."Mutational and gross deletion study of the MEN1 gene and correlation with clinical features in Spanish patients". J. Med. Genet.. 2003 , vol 40 , num 5 , p. e72 - e72
  • RUIZ LLORENTE, Sergio; , Robledo, M; , Pollan, M; , Gil, L; , Cebrian, A; , Ruiz, S; , Azanedo, M; , Benitez, J; , Menarguez, J; , Rojas, JM; ."Polymorphisms G691S/S904S of RET as genetic modifiers of MEN2A". Cancer Res.. 2003 , vol 63 , num 8 , p. 1814 - 1817
  • RUIZ LLORENTE, Sergio; , Ruiz-Llorente, S; , Arancha, C; , Cascón, A; , Osorio, A; , Benitez, J; , Martinez-Delgado, B; , Robledo, M; ."A rapid and easy method for multiple endocrine neoplasia type 1 mutation detection using conformation-sensitive gel electrophoresis". J. Hum. Genet.. 2002 , vol 47 , num 4 , p. 190 - 195
  • RUIZ LLORENTE, Sergio; , Cascón, A; , Ruiz-Llorente, S; , Cebrian, A; , Telleria, D; , Rivero, JC; , Diez, JJ; , Lopez-Ibarra, PJ; , Jaunsolo, MA; , Benitez, J; , Robledo, M; ."Identification of novel SDHD mutations in patients with phaeochromocytoma and/or paraganglioma". Eur. J. Hum. Genet.. 2002 , vol 10 , num 8 , p. 457 - 461
  • RUIZ LLORENTE, Sergio; , Cascón, A; , Cebrian, A; , Ruiz-Llorente, S; , Telleria, D; , Benitez, J; , Robledo, M; ."SDHB mutation analysis in familial and sporadic phaeochromocytoma identifies a novel mutation". J. Med. Genet.. 2002 , vol 39 , num 10 , p. E64 - E64

Artículos Electrónicos

No existen datos en este apartado

Congresos

No existen datos en este apartado

Tesis

  • QUIRALTE PULIDO, Miguel; "Perfiles proteómicos de exosomas peritoneales para la identificación de marcadores pronósticos y predictivos en carcinomas ováricos". Director: RUIZ LLORENTE, Sergio, , García-Donas, J, . Universidad San Pablo CEU. Fecha de lectura: 01/07/2023. .